The computational guide to Fiber-seq

This is the book for the computational tools of Fiber-seq which describes the two major software tools:

1. fibertools (ft) which is a CLI tool for creating and interacting with Fiber-seq BAM files.
   • the samtools of Fiber-seq
2. Fiber-seq Inferred Regulatory Elements which is a method for identifying regulatory elements on individual fibers and peak calling.
   • the MACS2 of Fiber-seq

Some Key features include:

• Predicting m6A sites from PacBio Fiber-seq data
• FIRE (Fiber-seq Inferred Regulatory Elements)
• Extracting Fiber-seq results into plain text files.
• Centering Fiber-seq results around a given position.
• pyft: Python bindings for fibertools

A quick start guide can be found here.

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